A1 Refereed original research article in a scientific journal
Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells
Authors: Pihlaja R, Takkinen J, Eskola O, Vasara J, Lopez-Picon FR, Haaparanta-Solin M, Rinne JO
Publisher: BIOMED CENTRAL LTD
Publication year: 2015
Journal: Journal of Neuroinflammation
Journal name in source: JOURNAL OF NEUROINFLAMMATION
Journal acronym: J NEUROINFLAMM
Article number: ARTN 81
Volume: 12
Number of pages: 6
ISSN: 1742-2094
eISSN: 1742-2094
DOI: https://doi.org/10.1186/s12974-015-0305-9
Conclusions: JZL184 decreased the proinflammatory reactions of microglia and reduced the total A beta burden and its precursors in the APdE9 mouse model. It also reduced the proinflammatory responses of microglia and astrocytes isolated from adult mice.
Downloadable publication This is an electronic reprint of the original article. |