A1 Refereed original research article in a scientific journal
Hemodynamic Bedside Monitoring Instrument with Pressure and Optical Sensors : Validation and Modality Comparison
Authors: Kaisti Matti, Panula Tuukka, Sirkiä Jukka-Pekka, Pänkäälä Mikko, Koivisto Tero, Niiranen Teemu, Kantola Ilkka
Publisher: Wiley-VCH
Publication year: 2024
Journal: Advanced Science
Journal name in source: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Journal acronym: Adv Sci (Weinh)
Article number: 2307718
Volume: 11
Issue: 24
eISSN: 2198-3844
DOI: https://doi.org/10.1002/advs.202307718
Web address : https://onlinelibrary.wiley.com/doi/10.1002/advs.202307718
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/393299112
Results from two independent clinical validation studies for measuring hemodynamics at the patient's bedside using a compact finger probe are reported. Technology comprises a barometric pressure sensor, and in one implementation, additionally, an optical sensor for photoplethysmography (PPG) is developed, which can be used to measure blood pressure and analyze rhythm, including the continuous detection of atrial fibrillation. The capabilities of the technology are shown in several form factors, including a miniaturized version resembling a common pulse oximeter to which the technology could be integrated in. Several main results are presented: i) the miniature finger probe meets the accuracy requirements of non-invasive blood pressure instrument validation standard, ii) atrial fibrillation can be detected during the blood pressure measurement and in a continuous recording, iii) a unique comparison between optical and pressure sensing mechanisms is provided, which shows that the origin of both modalities can be explained using a pressure-volume model and that recordings are close to identical between the sensors. The benefits and limitations of both modalities in hemodynamic monitoring are further discussed.
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