A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study




Tekijätvan Veen E, van der Jagt M, Cnossen MC, Maas AIR, de Beaufort ID, Menon DK, Citerio G, Stocchetti N, Rietdijk WJR, van Dijck JTJM, Kompanje EJO; and CENTER-TBI investigators and participants

Julkaisuvuosi2018

JournalCritical Care

Lehden akronyymiCrit Care.

Vuosikerta22

Sivujen määrä11

ISSN1466-609X

eISSN1364-8535

DOIhttps://doi.org/10.1186/s13054-018-2241-4

Verkko-osoite10.1186/s13054-018-2241-4

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/Publication/38871528


Tiivistelmä
BACKGROUND: 

We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation.

METHODS: 

Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study centers completed several questionnaires (response rate: 99%).

RESULTS: 

Regarding practices around brain death, we found agreement on the clinical evaluation (prerequisites and neurological assessment) for brain death determination (BDD) in 100% of the centers. However, ancillary tests were required for BDD in 64% of the centers. BDD for nondonor patients was deemed mandatory in 18% of the centers before withdrawing life-sustaining measures (LSM). Also, practices around postmortem organ donation varied. Organ donation after circulatory arrest was forbidden in 45% of the centers. When withdrawal of LSM was contemplated, in 67% of centers the patients with a ventricular drain in situ had this removed, either sometimes or all of the time.

CONCLUSIONS: 

This study showed both agreement and some regional differences regarding practices around brain death and postmortem organ donation. We hope our results help quantify and understand potential differences, and provide impetus for current dialogs toward further harmonization of practices around brain death and postmortem organ donation.


Ladattava julkaisu

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Last updated on 2024-26-11 at 10:21