A2 Refereed review article in a scientific journal

Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 1: Localized scleroderma, systemic sclerosis and overlap syndromes




AuthorsKnobler, Robert; Geroldinger-Simic, Marija; Kreuter, Alexander; Hunzelmann, Nicolas; Moinzadeh, Pia; Rongioletti, Franco; Denton, Christopher; Mouthon, Luc; Cutolo, Maurizio; Smith, Vanessa; Gabrielli, Armando; Bagot, Martine; Olesen, Anne B.; Foeldvari, Ivan; Jalili, Ahmad; Kähäri, Veli-Matti; Karpati, Sarolta; Kofoed, Kristian; Olszewska, Malgorzata; Panelius, Jaana; Quaglino, Pietro; Seneschal, Julien; Sticherling, Michael; Sunderkotter, Cord; Tanew, Adrian; Wolf, Peter; Worm, Margitta; Skrok, Anna; Rudnicka, Lidia; Krieg, Thomas

PublisherWiley-Blackwell

Publication year2024

Journal: Journal of the European Academy of Dermatology and Venereology

Journal name in sourceJOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Volume38

Issue7

First page 1251

Last page1280

ISSN0926-9959

eISSN1468-3083

DOIhttps://doi.org/10.1111/jdv.19912

Publication's open availability at the time of reportingNo Open Access

Publication channel's open availability Partially Open Access publication channel

Web address https://doi.org/10.1111/jdv.19912


Abstract

The term 'sclerosing diseases of the skin' comprises specific dermatological entities, which have fibrotic changes of the skin in common. These diseases mostly manifest in different clinical subtypes according to cutaneous and extracutaneous involvement and can sometimes be difficult to distinguish from each other. The present consensus provides an update to the 2017 European Dermatology Forum Guidelines, focusing on characteristic clinical and histopathological features, diagnostic scores and the serum autoantibodies most useful for differential diagnosis. In addition, updated strategies for the first- and advanced-line therapy of sclerosing skin diseases are addressed in detail. Part 1 of this consensus provides clinicians with an overview of the diagnosis and treatment of localized scleroderma (morphea), and systemic sclerosis including overlap syndromes.



Last updated on 09/03/2026 11:11:56 AM