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Total-Body PET/CT Applications in Cardiovascular Diseases: A Perspective Document of the SNMMI Cardiovascular Council




TekijätRiemer H.J.A. Slart, Frank M. Bengel, Cigdem Akincioglu, Jamieson M. Bourque, Wengen Chen, Marc R. Dweck, Marcus Hacker, Saurabh Malhotra, Edward J. Miller, Matthieu Pelletier-Galarneau, René R.S. Packard, Thomas H. Schindler, Richard L. Weinberg, Antti Saraste, Piotr J. Slomka

KustantajaSociety of Nuclear Medicine

Julkaisuvuosi2024

JournalJournal of Nuclear Medicine

Tietokannassa oleva lehden nimiJournal of Nuclear Medicine

Vuosikerta65

Numero4

ISSN0161-5505

eISSN0161-5505

DOIhttps://doi.org/10.2967/jnumed.123.266858

Verkko-osoitehttps://jnm.snmjournals.org/content/early/2024/02/22/jnumed.123.266858

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/387585286


Tiivistelmä
Digital PET/CT systems with a long axial field of view have become available and are emerging as the current state of the art. These new camera systems provide wider anatomic coverage, leading to major increases in system sensitivity. Preliminary results have demonstrated improvements in image quality and quantification, as well as substantial advantages in tracer kinetic modeling from dynamic imaging. These systems also potentially allow for low-dose examinations and major reductions in acquisition time. Thereby, they hold great promise to improve PET-based interrogation of cardiac physiology and biology. Additionally, the whole-body coverage enables simultaneous assessment of multiple organs and the large vascular structures of the body, opening new opportunities for imaging systemic mechanisms, disorders, or treatments and their interactions with the cardiovascular system as a whole. The aim of this perspective document is to debate the potential applications, challenges, opportunities, and remaining challenges of applying PET/CT with a long axial field of view to the field of cardiovascular disease.

Ladattava julkaisu

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.





Last updated on 2025-13-02 at 10:52