A1 Refereed original research article in a scientific journal
Enhancing identification of nonaffective psychosis in register-based studies
Authors: Holm Minna, Suokas Kimmo, Liukko Emmi, Lindgren Maija, Näätänen Petri, Kärkkäinen Jukka, Salokangas Raimo K. R., Suvisaari Jaana
Publisher: Springer Nature
Publication year: 2024
Journal: Schizophrenia
Journal name in source: Schizophrenia
Article number: 20
Volume: 10
Issue: 1
eISSN: 2754-6993
DOI: https://doi.org/10.1038/s41537-024-00444-6
Publication's open availability at the time of reporting: Open Access
Publication channel's open availability : Open Access publication channel
Web address : https://www.nature.com/articles/s41537-024-00444-6
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/387306928
The Finnish Quality of Psychosis Care Register assesses nonaffective psychosis (NAP) care, acknowledging treatment outside specialized psychiatric services. This approach, while providing a holistic view, raises concerns about diagnostic inaccuracies. Here, we studied situations where the register-based diagnosis might be inaccurate, and whether the first episode can be reliably identified using a 14-year wash-out period. People with first register-based NAP (ICD-10 F20-F29) between years 2010 and 2018 and without NAP diagnoses in 1996–2009 were identified from the Care Register for Health Care. A diagnosis of NAP was deemed unreliable before age 7, when dementia preceded NAP diagnosis, and when a NAP diagnosis had been assigned at admission or during psychiatric hospitalization but was not confirmed by discharge diagnosis. Despite a 14-year follow-back the first register diagnosis may miss the first treatment episode in older patients. Register-based studies on psychotic disorders should pay attention to exclusion criteria and to the definition of treatment onset. © The Author(s) 2024.
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