A1 Refereed original research article in a scientific journal
Impact of the COVID-19 Pandemic on Global TAVR Activity: The COVID-TAVI Study
Authors: Armario, Xavier; Carron, Jennifer; Simpkin, Andrew J.; Elhadi, Mohamed; Kennedy, Ciara; Abdel-Wahab, Mohamed; Bleiziffer, Sabine; Lefèvre, Thierry; Wolf, Alexander; Pilgrim, Thomas; Villablanca, Pedro A.; Blackman, Daniel J.; Van Mieghem, Nicolas M.; Hengstenberg, Christian; Swaans, Martin J.; Prendergast, Bernard D.; Patterson, Tiffany; Barbanti, Marco; Webb, John G.; Behan, Miles; Resar, Jon; Chen, Mao; Hildick-Smith, David; Spence, Mark S.; Zweiker, David; Bagur, Rodrigo; Teles, Rui; Ribichini, Flavio L.; Jagielak, Dariusz; Park, Duk-Woo; Kornowski, Ran; Wykrzykowska, Joanna J.; Bunc, Matjaz; Estévez-Loureiro, Rodrigo; Poon, Karl; Götberg, Matthias; Jeger, Raban V.; Ince, Hüseyin; Packer, Erik J. S.; Angelillis, Marco; Nombela-Franco, Luis; Guo, Yingqiang; Savontaus, Mikko; Al-Moghairi, Abdulrahman M.; Parasca, Catalina Andreea; Kliger, Chad; Roy, David; Molnár, Levente; Silva, Mariana; White, Jonathon; Yamamoto, Masanori; Carrilho-Ferreira, Pedro; Toggweiler, Stefan; Voudris, Vassileios; Ohno, Yohei; Rodrigues, Inês; Parma, Radosław; Ojeda, Soledad; Toutouzas, Kostas; Regueiro, Ander; Grygier, Marek; AlMerri, Khaled; Cruz-González, Ignacio; Fridrich, Viliam; de la Torre Hernández, José M.; Noble, Stephane; Kala, Petr; Asmarats, Lluis; Kurt, Ibrahim Halil; Bosmans, Johan; Erglis, Martin; Casserly, Ivan; Iskandarani, Dounia; Bhindi, Ravinay; Kefer, Joelle; Yin, Wei-Hsian; Rosseel, Liesbeth; Kim, Hyo-Soo; O'Connor, Stephen; Hellig, Farrel; Sztejfman, Matias; Mendiz, Oscar; Pineda, Andres M.; Seth, Ashok; Pllaha, Elton; de Brito, Fabio S.; Bajoras, Vilhelmas; Balghith, Mohammed A.; Lee, Michael; Eid-Lidt, Guering; Vandeloo, Bert; Vaz, Vinicius Daher; Alasnag, Mirvat; Ussia, Gian Paolo; Tay, Edgar; Mayol, Jorge; Gunasekaran, Sengottuvelu; Sardella, Gennaro; Buddhari, Wacin; Kao, Hsien-Li; Dager, Antonio; Tzikas, Apostolos; Gudmundsdottir, Ingibjörg J.; Edris, Ahmad; Gutiérrez, Jaikel Luis Abel; Arias, Eduardo A.; Al-Hijji, Mohammed; Ertürk, Mehmet; Conde-Vela, César; Boljević, Darko; Ferrero Guadagnoli, Adolfo; Hermlin, Toomas; ElGuindy, Ahmed M.; de Oliveira Lima-Filho, Moysés; de Moura Santos, Luciano; Perez, Luis; Maluenda, Gabriel; Akyüz, Ali Rıza; Alhaddad, Imad A.; Amin, Haitham; So, Chak-Yu; Al Nooryani, Arif A.; Vaca, Carlos; Albistur, Juan; Nguyen, Quang Ngoc; Arzamendi, Dabit; Grube, Eberhard; Modine, Thomas; Tchétché, Didier; Hayashida, Kentaro; Latib, Azeem; Makkar, Raj R.; Piazza, Nicolo; Søndergaard, Lars; McEvoy, John William; Mylotte, Darren
Publisher: American College of Cardiology Foundation
Publication year: 2024
Journal: JACC: Cardiovascular Interventions
Journal name in source: JACC: Cardiovascular Interventions
Volume: 17
Issue: 3
First page : 374
Last page: 387
ISSN: 1936-8798
eISSN: 1876-7605
DOI: https://doi.org/10.1016/j.jcin.2023.10.041
Publication's open availability at the time of reporting: No Open Access
Publication channel's open availability : Partially Open Access publication channel
Web address : https://www.sciencedirect.com/science/article/pii/S193687982301436X
Background The COVID-19 pandemic adversely affected health care systems. Patients in need of transcatheter aortic valve replacement (TAVR) are especially susceptible to treatment delays. Objectives The study sought to evaluate the impact of the COVID-19 pandemic on global TAVR activity. Methods This international registry reported monthly TAVR case volume in participating institutions prior to and during the COVID-19 pandemic (January 2018 to December 2021). Hospital-level information on public vs private, urban vs rural, and TAVR volume was collected, as was country-level information on socioeconomic status, COVID-19 incidence, and governmental public health responses. Results We included 130 centers from 61 countries, including 65,980 TAVR procedures. The first and second pandemic waves were associated with a significant reduction of 15% (P < 0.001) and 7% (P < 0.001) in monthly TAVR case volume, respectively, compared with the prepandemic period. The third pandemic wave was not associated with reduced TAVR activity. A greater reduction in TAVR activity was observed in Africa (−52%; P = 0.001), Central-South America (−33%; P < 0.001), and Asia (−29%; P < 0.001). Private hospitals (P = 0.005), urban areas (P = 0.011), low-volume centers (P = 0.002), countries with lower development (P < 0.001) and economic status (P < 0.001), higher COVID-19 incidence (P < 0.001), and more stringent public health restrictions (P < 0.001) experienced a greater reduction in TAVR activity. Conclusions TAVR procedural volume declined substantially during the first and second waves of the COVID-19 pandemic, especially in Africa, Central-South America, and Asia. National socioeconomic status, COVID-19 incidence, and public health responses were associated with treatment delays. This information should inform public health policy in case of future global health crises.
