A1 Refereed original research article in a scientific journal
Impact of the COVID-19 Pandemic on Global TAVR Activity: The COVID-TAVI Study
Authors: Armario Xavier, Carron Jennifer, Simpkin Andrew J., Elhadi Mohamed, Kennedy Ciara, Abdel-Wahab Mohamed, Bleiziffer Sabine, Lefèvre Thierry, Wolf Alexander, Pilgrim Thomas, Villablanca Pedro A., Blackman Daniel J., Van Mieghem Nicolas M., Hengstenberg Christian, Swaans Martin J., Prendergast Bernard D., Patterson Tiffany, Barbanti Marco, Webb John G., Behan Miles, Resar Jon, Chen Mao, Hildick-Smith David, Spence Mark S., Zweiker David, Bagur Rodrigo, Teles Rui, Ribichini Flavio L., Jagielak Dariusz, Park Duk-Woo, Kornowski Ran, Wykrzykowska Joanna J., Bunc Matjaz, Estévez-Loureiro Rodrigo, Poon Karl, Götberg Matthias, Jeger Raban V., Ince Hüseyin, Packer Erik J.S., Angelillis Marco, Nombela-Franco Luis, Guo Yingqiang, Savontaus Mikko, Al-Moghairi Abdulrahman M., Parasca Catalina Andreea, Kliger Chad, Roy David, Molnár Levente, Silva Mariana, White Jonathon, Yamamoto Masanori, Carrilho-Ferreira Pedro, Toggweiler Stefan, Voudris Vassileios, Ohno Yohei, Rodrigues Inês, Parma Radosław, Ojeda Soledad, Toutouzas Kostas, Regueiro Ander, Grygier Marek, AlMerri Khaled, Cruz-González Ignacio, Fridrich Viliam, de la Torre Hernández José M., Noble Stephane, Kala Petr, Asmarats Lluis, Kurt Ibrahim Halil, Bosmans Johan, Erglis Martin, Casserly Ivan, Iskandarani Dounia, Bhindi Ravinay, Kefer Joelle, Yin Wei-Hsian, Rosseel Liesbeth, Kim Hyo-Soo, O'Connor Stephen, Hellig Farrel, Sztejfman Matias, Mendiz Oscar, Pineda Andres M., Seth Ashok, Pllaha Elton, de Brito Fabio S., Bajoras Vilhelmas, Balghith Mohammed A., Lee Michael, Eid-Lidt Guering, Vandeloo Bert, Vaz Vinicius Daher, Alasnag Mirvat, Ussia Gian Paolo, Tay Edgar, Mayol Jorge, Gunasekaran Sengottuvelu, Sardella Gennaro, Buddhari Wacin, Kao Hsien-Li, Dager Antonio, Tzikas Apostolos, Gudmundsdottir Ingibjörg J., Edris Ahmad, Gutiérrez Jaikel Luis Abel, Arias Eduardo A., Al-Hijji Mohammed, Ertürk Mehmet, Conde-Vela César, Boljević Darko, Ferrero Guadagnoli Adolfo, Hermlin Toomas, ElGuindy Ahmed M., Lima-Filho Moysés de Oliveira, de Moura Santos Luciano, Perez Luis, Maluenda Gabriel, Akyüz Ali Rıza, Alhaddad Imad A., Amin Haitham, So Chak-Yu, Al Nooryani Arif A., Vaca Carlos, Albistur Juan, Nguyen Quang Ngoc, Arzamendi Dabit, Grube Eberhard, Modine Thomas, Tchétché Didier, Hayashida Kentaro, Latib Azeem, Makkar Raj R., Piazza Nicolo, Søndergaard Lars, McEvoy John William, Mylotte Darren
Publisher: American College of Cardiology Foundation
Publication year: 2024
Journal: JACC: Cardiovascular Interventions
Journal name in source: JACC: Cardiovascular Interventions
Volume: 17
Issue: 3
First page : 374
Last page: 387
ISSN: 1936-8798
eISSN: 1876-7605
DOI: https://doi.org/10.1016/j.jcin.2023.10.041
Web address : https://www.sciencedirect.com/science/article/pii/S193687982301436X
Background The COVID-19 pandemic adversely affected health care systems. Patients in need of transcatheter aortic valve replacement (TAVR) are especially susceptible to treatment delays. Objectives The study sought to evaluate the impact of the COVID-19 pandemic on global TAVR activity. Methods This international registry reported monthly TAVR case volume in participating institutions prior to and during the COVID-19 pandemic (January 2018 to December 2021). Hospital-level information on public vs private, urban vs rural, and TAVR volume was collected, as was country-level information on socioeconomic status, COVID-19 incidence, and governmental public health responses. Results We included 130 centers from 61 countries, including 65,980 TAVR procedures. The first and second pandemic waves were associated with a significant reduction of 15% (P < 0.001) and 7% (P < 0.001) in monthly TAVR case volume, respectively, compared with the prepandemic period. The third pandemic wave was not associated with reduced TAVR activity. A greater reduction in TAVR activity was observed in Africa (−52%; P = 0.001), Central-South America (−33%; P < 0.001), and Asia (−29%; P < 0.001). Private hospitals (P = 0.005), urban areas (P = 0.011), low-volume centers (P = 0.002), countries with lower development (P < 0.001) and economic status (P < 0.001), higher COVID-19 incidence (P < 0.001), and more stringent public health restrictions (P < 0.001) experienced a greater reduction in TAVR activity. Conclusions TAVR procedural volume declined substantially during the first and second waves of the COVID-19 pandemic, especially in Africa, Central-South America, and Asia. National socioeconomic status, COVID-19 incidence, and public health responses were associated with treatment delays. This information should inform public health policy in case of future global health crises.
