A1 Refereed original research article in a scientific journal

Early clinical experience with a degraded 4 MeV electron beam in radiotherapy of superficial basal cell carcinoma




AuthorsValve Assi, Koskenmies Sari, Tenhunen Mikko, Nurmi Heidi, Hernberg Micaela, Salminen Samuli, Anttonen Anu

PublisherElsevier

Publication year2023

Journal: Physics and Imaging in Radiation Oncology

Journal name in sourcePhysics and Imaging in Radiation Oncology

Article number 100487

Volume27

ISSN2405-6316

eISSN2405-6316

DOIhttps://doi.org/10.1016/j.phro.2023.100487

Publication's open availability at the time of reportingOpen Access

Publication channel's open availability Open Access publication channel

Web address https://doi.org/10.1016/j.phro.2023.100487

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/381255499

Self-archived copy's licenceCC BY NC ND

Self-archived copy's versionPublisher`s PDF


Abstract
The most common non-melanoma skin cancer is basal cell carcinoma (BCC). Surgery is the gold standard treatment but also non-surgical alternatives are needed. The purpose of this work was to present the early clinical experiences of degraded 4 MeV electron beam as a treatment method for superficial BCC. Twelve patients underwent two weeks radiation therapy treatment with either 5 × 7 Gy or 2 × 12 Gy. There were no significant differences in treatment outcome with different fractionations or lesion locations. The degraded beam method is a safe and valid non-surgical solution for suitable patients with superficial lesions.

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