This paper presents two gesture-based user interfaces which were designed for a 3D design review in virtual reality (VR) with inspiration drawn from the shipbuilding industry’s need to streamline and make their processes more sustainable. The user interfaces, one focusing on single-hand (unimanual) gestures and the other focusing on dual-handed (bimanual) usage, are tested as a case study using 13 tasks. The unimanual approach attempts to provide a higher degree of flexibility, while the bimanual approach seeks to provide more control over the interaction. The interfaces were developed for the Meta Quest 2 VR headset using the Unity game engine. Hand-tracking (HT) is utilized due to potential usability benefits in comparison to standard controller-based user interfaces, which lack intuitiveness regarding the controls and can cause more strain. The user interfaces were tested with 25 test users, and the results indicate a preference toward the one-handed user interface with little variation in test user categories. Additionally, the testing order, which was counterbalanced, had a statistically significant impact on the preference and performance, indicating that learning novel interaction mechanisms requires an adjustment period for reliable results. VR sickness was also strongly experienced by a few users, and there were no signs that gesture controls would significantly alleviate it.