Contaminants produced by human activities are found all over the globe due to atmospheric and oceanographic movements. As a result, humans, wildlife and our environment are exposed to multiple contaminants worldwide. The exposure effects of these contaminant cocktails on human and wildlife health is of increasing concern within a one health perspective. Among these contaminants, endocrine disrupting chemicals (EDCs) may cause a large array of adverse effects. Birds are considered model bioindicators of environmental health. EDCs affect their behaviour, fecundity, growth, survival, disease resistance, sex determination, and other components of life history. Among birds, ducks are of particular interest to examine EDCs exposure and its effects because ducks are widespread, well monitored, and their ecology and physiology are well known. They also use surface water with different levels of contamination like marine waters, and agricultural and urban wetlands. Moreover, in recent years, an increased sex ratio bias towards males has been observed in several duck species. In this context, the DISRUPT project (sites.utu.fi/disrupt/) investigates the exposure and biological effects of EDCs in breeding female ducks, and their eggs and ducklings. We have established that Finnish breeding female ducks are contaminated by a mixture of EDCs including per- and polyfluoroalkyl substances (PFASs), among which some of emerging concern, phthalates, benzophenones, bisphenols, benzotriazoles, benzothiazoles, parabens and heavy metals such as lead (Pb). We also have shown a maternal transfer of EDCs from hens to their eggs. Our results have implications in the context of observed hatching failure and avian influenza outbreaks.