A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Inflammation and Increased Myxovirus Resistance Protein A Expression in Thyroid Tissue in the Early Stages of Hashimoto's Thyroiditis
Tekijät: Hammerstad SS, Jahnsen FL, Tauriainen S, Hyoty H, Paulsen T, Norheim I, Dahl-Jorgensen K
Kustantaja: MARY ANN LIEBERT INC
Julkaisuvuosi: 2013
Journal: Thyroid
Tietokannassa oleva lehden nimi: THYROID
Lehden akronyymi: THYROID
Numero sarjassa: 3
Vuosikerta: 23
Numero: 3
Aloitussivu: 334
Lopetussivu: 341
Sivujen määrä: 8
ISSN: 1050-7256
DOI: https://doi.org/10.1089/thy.2012.0264
Tiivistelmä
Conclusion: The inflammatory reaction in the thyroid gland is a very early event in the pathogenesis of HT. The increased expression of MxA in the inflamed tissue suggests that type I IFN plays a role in disease development. Whether this is virus-dependent needs to be explored in further studies.
Conclusion: The inflammatory reaction in the thyroid gland is a very early event in the pathogenesis of HT. The increased expression of MxA in the inflamed tissue suggests that type I IFN plays a role in disease development. Whether this is virus-dependent needs to be explored in further studies.
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