A1 Refereed original research article in a scientific journal
Inflammation and Increased Myxovirus Resistance Protein A Expression in Thyroid Tissue in the Early Stages of Hashimoto's Thyroiditis
Authors: Hammerstad SS, Jahnsen FL, Tauriainen S, Hyoty H, Paulsen T, Norheim I, Dahl-Jorgensen K
Publisher: MARY ANN LIEBERT INC
Publication year: 2013
Journal: Thyroid
Journal name in source: THYROID
Journal acronym: THYROID
Number in series: 3
Volume: 23
Issue: 3
First page : 334
Last page: 341
Number of pages: 8
ISSN: 1050-7256
DOI: https://doi.org/10.1089/thy.2012.0264(external)
Abstract
Conclusion: The inflammatory reaction in the thyroid gland is a very early event in the pathogenesis of HT. The increased expression of MxA in the inflamed tissue suggests that type I IFN plays a role in disease development. Whether this is virus-dependent needs to be explored in further studies.
Conclusion: The inflammatory reaction in the thyroid gland is a very early event in the pathogenesis of HT. The increased expression of MxA in the inflamed tissue suggests that type I IFN plays a role in disease development. Whether this is virus-dependent needs to be explored in further studies.