Brown adipose tissue functions in humans
: Virtanen KA, Lichtenbelt WDV, Nuutila P
Publisher: ELSEVIER SCIENCE BV
: 2013
: Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
: BBA-MOL CELL BIOL L
: 5
: 1831
: 5
: 1004
: 1008
: 5
: 1388-1981
DOI: https://doi.org/10.1016/j.bbalip.2012.12.011
Human adults have functionally active BAT. The metabolic function can be reliably measured in vivo using modern imaging modalities (namely PET/CT). Cold seems to be one of the most potent stimulators of BAT metabolic activity but other stimulators (for example insulin) are actively studied. Obesity is related to lower metabolic activity of BAT but it may be reversed after successful weight reduction such as after bariatric surgery. This article is part of a Special Issue entitled Brown and White Fat: From Signaling to Disease. (C) 2013 Elsevier B.V. All rights reserved.