A1 Refereed original research article in a scientific journal
Brown adipose tissue functions in humans
Authors: Virtanen KA, Lichtenbelt WDV, Nuutila P
Publisher: ELSEVIER SCIENCE BV
Publication year: 2013
Journal: Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
Journal name in source: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Journal acronym: BBA-MOL CELL BIOL L
Number in series: 5
Volume: 1831
Issue: 5
First page : 1004
Last page: 1008
Number of pages: 5
ISSN: 1388-1981
DOI: https://doi.org/10.1016/j.bbalip.2012.12.011
Abstract
Human adults have functionally active BAT. The metabolic function can be reliably measured in vivo using modern imaging modalities (namely PET/CT). Cold seems to be one of the most potent stimulators of BAT metabolic activity but other stimulators (for example insulin) are actively studied. Obesity is related to lower metabolic activity of BAT but it may be reversed after successful weight reduction such as after bariatric surgery. This article is part of a Special Issue entitled Brown and White Fat: From Signaling to Disease. (C) 2013 Elsevier B.V. All rights reserved.
Human adults have functionally active BAT. The metabolic function can be reliably measured in vivo using modern imaging modalities (namely PET/CT). Cold seems to be one of the most potent stimulators of BAT metabolic activity but other stimulators (for example insulin) are actively studied. Obesity is related to lower metabolic activity of BAT but it may be reversed after successful weight reduction such as after bariatric surgery. This article is part of a Special Issue entitled Brown and White Fat: From Signaling to Disease. (C) 2013 Elsevier B.V. All rights reserved.
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