A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Effects of tolterodine on afferent neurotransmission in normal and resiniferatoxin treated conscious rats
Tekijät: Hedlund P, Streng T, Lee T, Andersson KE
Kustantaja: ELSEVIER SCIENCE INC
Julkaisuvuosi: 2007
Lehti:Journal of Urology
Tietokannassa oleva lehden nimiJOURNAL OF UROLOGY
Lehden akronyymi: J UROLOGY
Vuosikerta: 178
Numero: 1
Aloitussivu: 326
Lopetussivu: 331
Sivujen määrä: 6
ISSN: 0022-5347
DOI: https://doi.org/10.1016/j.juro.2007.03.006
Tiivistelmä
Conclusions: Tolterodine increased the micturition interval and bladder capacity in controls and in resiniferatoxin treated animals, suggesting that these effects were exerted independently of resiniferatoxin sensitive afferents. Tolterodine did not decrease the contractile effects of apomorphine at the doses used, suggesting that the drug had no effect on efferent neurotransmission during voiding.
Conclusions: Tolterodine increased the micturition interval and bladder capacity in controls and in resiniferatoxin treated animals, suggesting that these effects were exerted independently of resiniferatoxin sensitive afferents. Tolterodine did not decrease the contractile effects of apomorphine at the doses used, suggesting that the drug had no effect on efferent neurotransmission during voiding.
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