Nasopharyngeal Bacterial Colonization and Gene Polymorphisms of Mannose-Binding Lectin and Toll-Like Receptors 2 and 4 in Infants



: Vuononvirta J, Toivonen L, Grondahl-Yli-Hannuksela K, Barkoff AM, Lindholm L, Mertsola J, Peltola V, He QS

Publisher: PUBLIC LIBRARY SCIENCE

: 2011

: PLoS ONE

: PLOS ONE

: PLOS ONE

: ARTN e26198

: 10

: 6

: 10

: e 26198

: 5

: 1932-6203

DOI: https://doi.org/10.1371/journal.pone.0026198


Conclusions: Our study suggests that there is an association between nasopharyngeal bacterial colonization and genetic variation of MBL, TLR2 and TLR4 in young infants. This finding supports a role for these genetic variations in susceptibility of children to respiratory infections.




Last updated on 2024-26-11 at 15:43