Nasopharyngeal Bacterial Colonization and Gene Polymorphisms of Mannose-Binding Lectin and Toll-Like Receptors 2 and 4 in Infants - UTU Research Portal

A1 Refereed original research article in a scientific journal

Nasopharyngeal Bacterial Colonization and Gene Polymorphisms of Mannose-Binding Lectin and Toll-Like Receptors 2 and 4 in Infants

Authors: Vuononvirta J, Toivonen L, Grondahl-Yli-Hannuksela K, Barkoff AM, Lindholm L, Mertsola J, Peltola V, He QS

Publisher: PUBLIC LIBRARY SCIENCE

Publication year: 2011

Journal: PLoS ONE

Journal name in source: PLOS ONE

Journal acronym: PLOS ONE

Article number: ARTN e26198

Number in series: 10

Volume: 6

Issue: 10

First page : e 26198

Number of pages: 5

ISSN: 1932-6203

DOI: https://doi.org/10.1371/journal.pone.0026198

Abstract

Conclusions: Our study suggests that there is an association between nasopharyngeal bacterial colonization and genetic variation of MBL, TLR2 and TLR4 in young infants. This finding supports a role for these genetic variations in susceptibility of children to respiratory infections.