A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Voriconazole and fluconazole increase the exposure to oral diazepam
Tekijät: Saari TI, Laine K, Bertilsson L, Neuvonen PJ, Olkkola KT
Kustantaja: SPRINGER
Julkaisuvuosi: 2007
Journal: European Journal of Clinical Pharmacology
Tietokannassa oleva lehden nimi: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Lehden akronyymi: EUR J CLIN PHARMACOL
Vuosikerta: 63
Numero: 10
Aloitussivu: 941
Lopetussivu: 949
Sivujen määrä: 9
ISSN: 0031-6970
DOI: https://doi.org/10.1007/s00228-007-0350-0
Tiivistelmä
Conclusion Both voriconazole and fluconazole considerably increase the exposure to diazepam. Recurrent administration of diazepam increases the risk of clinically significant interactions during voriconazole or fluconazole treatment, because the elimination of diazepam is impaired significantly.
Conclusion Both voriconazole and fluconazole considerably increase the exposure to diazepam. Recurrent administration of diazepam increases the risk of clinically significant interactions during voriconazole or fluconazole treatment, because the elimination of diazepam is impaired significantly.
Ladattava julkaisu This is an electronic reprint of the original article. |