A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Age-dependent cyclooxygenase-2 induction and neuronal damage after status epilepticus in the postnatal rat hippocampus
Tekijät: Jarvela JT, Lopez-Picon FR, Holopainen IE
Kustantaja: BLACKWELL PUBLISHING
Julkaisuvuosi: 2008
Journal: Epilepsia
Tietokannassa oleva lehden nimi: EPILEPSIA
Lehden akronyymi: EPILEPSIA
Vuosikerta: 49
Numero: 5
Aloitussivu: 832
Lopetussivu: 841
Sivujen määrä: 10
ISSN: 0013-9580
DOI: https://doi.org/10.1111/j.1528-1167.2007.01454.x
Tiivistelmä
Discussion: Our results suggest that SE provokes age-specific effects on COX-2 expression. This together with the activation of putative inflammatory processes may contribute to neuronal cell death in the hippocampus of postnatal rats, whereas caspase-dependent apoptosis seems not to be involved in the death process.
Discussion: Our results suggest that SE provokes age-specific effects on COX-2 expression. This together with the activation of putative inflammatory processes may contribute to neuronal cell death in the hippocampus of postnatal rats, whereas caspase-dependent apoptosis seems not to be involved in the death process.