IL-10 Gene Polymorphisms Are Associated with Post-Bronchiolitis Lung Function Abnormalities at Six Years of Age

: Lauhkonen E, Koponen P, Terasjarvi J, Grondahl-Yli-Hannuksela K, Vuononvirta J, Nuolivirta K, Toikka JO, Helminen M, He QS, Korppi M

Publisher: PUBLIC LIBRARY SCIENCE

: 2015

: PLoS ONE

: PLOS ONE

: ARTN e0140799

: 10

: 11

: 1932-6203

DOI: https://doi.org/10.1371/journal.pone.0140799

Low-IL-10-producing polymorphisms in the IL-10 encoding gene were associated with obstructive lung function parameters, suggesting an important role for IL-10 in development of lung function deficit in early bronchiolitis patients.