IL-10 Gene Polymorphisms Are Associated with Post-Bronchiolitis Lung Function Abnormalities at Six Years of Age - UTU Research Portal

A1 Refereed original research article in a scientific journal

IL-10 Gene Polymorphisms Are Associated with Post-Bronchiolitis Lung Function Abnormalities at Six Years of Age

Authors: Lauhkonen E, Koponen P, Terasjarvi J, Grondahl-Yli-Hannuksela K, Vuononvirta J, Nuolivirta K, Toikka JO, Helminen M, He QS, Korppi M

Publisher: PUBLIC LIBRARY SCIENCE

Publication year: 2015

Journal: PLoS ONE

Journal name in source: PLOS ONE

Journal acronym: PLOS ONE

Article number: ARTN e0140799

Volume: 10

Issue: 10

Number of pages: 11

ISSN: 1932-6203

DOI: https://doi.org/10.1371/journal.pone.0140799(external)

Abstract

Low-IL-10-producing polymorphisms in the IL-10 encoding gene were associated with obstructive lung function parameters, suggesting an important role for IL-10 in development of lung function deficit in early bronchiolitis patients.