Recombinant Human FSH Treatment Outcomes in Five Boys With Severe Congenital Hypogonadotropic Hypogonadism
: Kohva E, Huopio H, Hero M, Miettinen PJ, Vaaralahti K, Sidoroff V, Toppari J, Raivio T
: 2018
: Journal of the Endocrine Society
: Journal of the Endocrine Society
: J Endocr Soc
: 2
: 12
: 1345
: 1356
: 12
: 2472-1972
: 2472-1972
DOI: https://doi.org/10.1210/js.2018-00225
: https://research.utu.fi/converis/portal/detail/Publication/36931150
Conclusions
Spermatogenesis can be induced with gonadotropins even in boys with HH who have extremely small testes, and despite low-dose T treatment given in early puberty. Induction of puberty with gonadotropins allows preservation of fertility.