A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Urodynamic changes in a noble rat model for nonbacterial prostatic inflammation
Tekijät: Bernoulli J, Yatkin E, Talvitie EM, Santti R, Streng T
Kustantaja: WILEY-LISS
Julkaisuvuosi: 2007
Lehti:: Prostate
Tietokannassa oleva lehden nimi: PROSTATE
Lehden akronyymi: PROSTATE
Vuosikerta: 67
Numero: 8
Aloitussivu: 888
Lopetussivu: 899
Sivujen määrä: 12
ISSN: 0270-4137
DOI: https://doi.org/10.1002/pros.20567
Tiivistelmä
CONCLUSIONS. Elevated estrogen concentration was essential for the gradual development of prostatic inflammation. The profile and location of inflammatory cells suggest that prostatic vasculature is one of the sites of estrogen action. Urodynamic changes which developed in association with glandular inflammation indicated abnormal bladder function, reflecting an incipient obstruction.
CONCLUSIONS. Elevated estrogen concentration was essential for the gradual development of prostatic inflammation. The profile and location of inflammatory cells suggest that prostatic vasculature is one of the sites of estrogen action. Urodynamic changes which developed in association with glandular inflammation indicated abnormal bladder function, reflecting an incipient obstruction.