A1 Refereed original research article in a scientific journal
Urodynamic changes in a noble rat model for nonbacterial prostatic inflammation
Authors: Bernoulli J, Yatkin E, Talvitie EM, Santti R, Streng T
Publisher: WILEY-LISS
Publication year: 2007
Journal:: Prostate
Journal name in source: PROSTATE
Journal acronym: PROSTATE
Volume: 67
Issue: 8
First page : 888
Last page: 899
Number of pages: 12
ISSN: 0270-4137
DOI: https://doi.org/10.1002/pros.20567
Abstract
CONCLUSIONS. Elevated estrogen concentration was essential for the gradual development of prostatic inflammation. The profile and location of inflammatory cells suggest that prostatic vasculature is one of the sites of estrogen action. Urodynamic changes which developed in association with glandular inflammation indicated abnormal bladder function, reflecting an incipient obstruction.
CONCLUSIONS. Elevated estrogen concentration was essential for the gradual development of prostatic inflammation. The profile and location of inflammatory cells suggest that prostatic vasculature is one of the sites of estrogen action. Urodynamic changes which developed in association with glandular inflammation indicated abnormal bladder function, reflecting an incipient obstruction.