A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Steroid-responsive encephalopathy with a peculiar CSF biomarker profile in an 89-year-old man
Tekijät: Sipilä J., Rissanen E., Korpela J., Päivärinta M.
Kustantaja: Oxford University Press
Julkaisuvuosi: 2018
Journal: Oxford Medical Case Reports
Tietokannassa oleva lehden nimi: Oxford Medical Case Reports
Artikkelin numero: omy073
Vuosikerta: 2018
Numero: 10
Aloitussivu: 339
Lopetussivu: 341
ISSN: 2053-8855
eISSN: 2053-8855
DOI: https://doi.org/10.1093/omcr/omy073
Verkko-osoite: https://academic.oup.com/omcr/article/2018/10/omy073/5106147
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/36683014
Being treatable, steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), or Hashimoto’s encephalopathy, should be distinguished from untreatable conditions. Our patient was a previously healthy 89-year-old man, who presented with cognitive and balance deterioration over several months. His cerebrospinal fluid (CSF) examination was positive for protein 14-3-3 but no other test suggested Creutzfeldt–Jacob disease. His condition improved markedly, although not fully, with intravenous corticosteroids. In control CSF sampling, protein 14-3-3 was negative but a biomarker signature consistent with Alzheimer’s disease was observed. SREAT should be considered also in the very elderly in case of subacute encephalopathy.
Ladattava julkaisu This is an electronic reprint of the original article. |