Avidity of anti-Yersinia antibodies in yersiniosis patients with and without Yersinia-triggered reactive arthritis



: Lahesmaa-Rantala R, Lehtonen OP, Granfors K, Toivanen A

: 1987

: Arthritis and Rheumatism

: Arthritis and rheumatism

: Arthritis Rheum

: 30

: 10

: 1176

: 81

: 6

: 0004-3591

DOI: https://doi.org/10.1002/art.1780301015


Avidity of IgM, IgG, and IgA class anti-Yersinia antibodies was compared in sera of 22 patients with yersiniosis and subsequent reactive arthritis versus sera of 22 patients without postinfection complications. An enzyme-linked immunosorbent assay was used for antibody determination. Less than 2 months after onset of the infection, the patients with arthritis had fewer high-avidity IgM antibodies against the bacterial lipopolysaccharide (P = 0.035) and more high-avidity IgA antibodies against bacterial cell extract (P = 0.039) than did the patients without arthritis. This difference increased with time.



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