A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Avidity of anti-Yersinia antibodies in yersiniosis patients with and without Yersinia-triggered reactive arthritis
Tekijät: Lahesmaa-Rantala R, Lehtonen OP, Granfors K, Toivanen A
Julkaisuvuosi: 1987
Journal: Arthritis and Rheumatism
Tietokannassa oleva lehden nimi: Arthritis and rheumatism
Lehden akronyymi: Arthritis Rheum
Vuosikerta: 30
Numero: 10
Aloitussivu: 1176
Lopetussivu: 81
Sivujen määrä: 6
ISSN: 0004-3591
DOI: https://doi.org/10.1002/art.1780301015
Tiivistelmä
Avidity of IgM, IgG, and IgA class anti-Yersinia antibodies was compared in sera of 22 patients with yersiniosis and subsequent reactive arthritis versus sera of 22 patients without postinfection complications. An enzyme-linked immunosorbent assay was used for antibody determination. Less than 2 months after onset of the infection, the patients with arthritis had fewer high-avidity IgM antibodies against the bacterial lipopolysaccharide (P = 0.035) and more high-avidity IgA antibodies against bacterial cell extract (P = 0.039) than did the patients without arthritis. This difference increased with time.
Avidity of IgM, IgG, and IgA class anti-Yersinia antibodies was compared in sera of 22 patients with yersiniosis and subsequent reactive arthritis versus sera of 22 patients without postinfection complications. An enzyme-linked immunosorbent assay was used for antibody determination. Less than 2 months after onset of the infection, the patients with arthritis had fewer high-avidity IgM antibodies against the bacterial lipopolysaccharide (P = 0.035) and more high-avidity IgA antibodies against bacterial cell extract (P = 0.039) than did the patients without arthritis. This difference increased with time.
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