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APOE-epsilon4 predicts dementia but not other psychiatric disorders after traumatic brain injury
Tekijät: Koponen S, Taiminen T, Kairisto V, Portin R, Isoniemi H, Hinkka S, Tenovuo O
Julkaisuvuosi: 2004
Lehti:: Neurology
Tietokannassa oleva lehden nimi: Neurology
Lehden akronyymi: Neurology
Vuosikerta: 63
Numero: 4
Aloitussivu: 749
Lopetussivu: 50
Sivujen määrä: 2
ISSN: 0028-3878
eISSN: 1526-632X
DOI: https://doi.org/10.1212/01.WNL.0000134603.57107.2F
Tiivistelmä
The authors studied the association between APOE-epsilon4 genotype and axis I and II psychiatric disorders an average of 30 years after traumatic brain injury. Sixty patients were dichotomized into subjects with and without APOE-epsilon4 allele. Dementia and subclinical dementia were significantly more common with the presence of APOE-epsilon4. The occurrence of other psychiatric disorders did not differ between patients with and without APOE-epsilon4 allele.
The authors studied the association between APOE-epsilon4 genotype and axis I and II psychiatric disorders an average of 30 years after traumatic brain injury. Sixty patients were dichotomized into subjects with and without APOE-epsilon4 allele. Dementia and subclinical dementia were significantly more common with the presence of APOE-epsilon4. The occurrence of other psychiatric disorders did not differ between patients with and without APOE-epsilon4 allele.
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