A1 Refereed original research article in a scientific journal
APOE-epsilon4 predicts dementia but not other psychiatric disorders after traumatic brain injury
Authors: Koponen S, Taiminen T, Kairisto V, Portin R, Isoniemi H, Hinkka S, Tenovuo O
Publication year: 2004
Journal: Neurology
Journal name in source: Neurology
Journal acronym: Neurology
Volume: 63
Issue: 4
First page : 749
Last page: 50
Number of pages: 2
ISSN: 0028-3878
eISSN: 1526-632X
DOI: https://doi.org/10.1212/01.WNL.0000134603.57107.2F
Abstract
The authors studied the association between APOE-epsilon4 genotype and axis I and II psychiatric disorders an average of 30 years after traumatic brain injury. Sixty patients were dichotomized into subjects with and without APOE-epsilon4 allele. Dementia and subclinical dementia were significantly more common with the presence of APOE-epsilon4. The occurrence of other psychiatric disorders did not differ between patients with and without APOE-epsilon4 allele.
The authors studied the association between APOE-epsilon4 genotype and axis I and II psychiatric disorders an average of 30 years after traumatic brain injury. Sixty patients were dichotomized into subjects with and without APOE-epsilon4 allele. Dementia and subclinical dementia were significantly more common with the presence of APOE-epsilon4. The occurrence of other psychiatric disorders did not differ between patients with and without APOE-epsilon4 allele.
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