Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women



: Gerdhem P, Ivaska KK, Isaksson A, Pettersson K, Vaananen HK, Obrant KJ, Akesson K

Publisher: AMER SOC BONE & MINERAL RES

: 2007

: Journal of Bone and Mineral Research

: JOURNAL OF BONE AND MINERAL RESEARCH

: J BONE MINER RES

: 22

: 1

: 127

: 134

: 8

: 0884-0431

DOI: https://doi.org/10.1359/JBMR.061003


Homocysteine has been suggested to be a risk factor for fracture, but the causal relationship is not clear. In 996 women from the OPRA study, high homocysteine level was associated with high bone marker levels and low BMD at baseline. During a mean 7-year follow-up, high homocysteine level was associated with mortality, but no clear association to fracture risk existed.



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