A1 Refereed original research article in a scientific journal

Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women



Authors: Gerdhem P, Ivaska KK, Isaksson A, Pettersson K, Vaananen HK, Obrant KJ, Akesson K

Publisher: AMER SOC BONE & MINERAL RES

Publication year: 2007

Journal: Journal of Bone and Mineral Research

Journal name in source: JOURNAL OF BONE AND MINERAL RESEARCH

Journal acronym: J BONE MINER RES

Volume: 22

Issue: 1

First page : 127

Last page: 134

Number of pages: 8

ISSN: 0884-0431

DOI: https://doi.org/10.1359/JBMR.061003


Abstract
Homocysteine has been suggested to be a risk factor for fracture, but the causal relationship is not clear. In 996 women from the OPRA study, high homocysteine level was associated with high bone marker levels and low BMD at baseline. During a mean 7-year follow-up, high homocysteine level was associated with mortality, but no clear association to fracture risk existed.



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