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SHORT-TERM USE OF AMOXICILLIN-CLAVULANATE DURING UPPER RESPIRATORY-TRACT INFECTION FOR PREVENTION OF ACUTE OTITIS-MEDIA
Tekijät: HEIKKINEN T, RUUSKANEN O, ZIEGLER T, WARIS M, PUHAKKA H
Kustantaja: MOSBY-ELSEVIER
Julkaisuvuosi: 1995
Journal: Journal of Pediatrics
Tietokannassa oleva lehden nimi: JOURNAL OF PEDIATRICS
Lehden akronyymi: J PEDIATR-US
Vuosikerta: 126
Numero: 2
Aloitussivu: 313
Lopetussivu: 316
Sivujen määrä: 4
ISSN: 0022-3476
DOI: https://doi.org/10.1016/S0022-3476(95)70569-4
Tiivistelmä
We performed a randomized, double-blind, placebo-controlled study to determine whether acute otitis media could be prevented by antibiotic therapy initiated promptly after the appearance of symptoms of upper respiratory tract infection, One hundred four children aged 1 to 4 years received a 7-day course of either amoxicillin-clavulanate or placebo, Acute otitis media developed in 9 (18%) of the 50 children receiving amoxicillin clavulanate and in 12 (22%) of the 54 children receiving placebo (p = 0.59).
We performed a randomized, double-blind, placebo-controlled study to determine whether acute otitis media could be prevented by antibiotic therapy initiated promptly after the appearance of symptoms of upper respiratory tract infection, One hundred four children aged 1 to 4 years received a 7-day course of either amoxicillin-clavulanate or placebo, Acute otitis media developed in 9 (18%) of the 50 children receiving amoxicillin clavulanate and in 12 (22%) of the 54 children receiving placebo (p = 0.59).
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