Drug Target Commons 2.0: a community platform for systematic analysis of drug target interaction profiles

: Ziaur Rehman Tanoli, Zaid Alam, Markus Vähä-Koskela, Balaguru Ravikumar, Alina Malyutina, Alok Jaiswal, Jing Tang, Krister Wennerberg, Tero Aittokallio

Publisher: OXFORD UNIV PRESS

: 2018

: Database: The Journal of Biological Databases and Curation

: DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION

: DATABASE-OXFORD

: ARTN bay083

: 1

: 13

: 1758-0463

DOI: https://doi.org/10.1093/database/bay083

: https://academic.oup.com/database/article/doi/10.1093/database/bay083/5096727

: https://research.utu.fi/converis/portal/detail/Publication/36126986

Drug Target Commons (DTC) is a web platform (database with user interface) for community-driven bioactivity data integration and standardization for comprehensive mapping, reuse and analysis of compound-target interaction profiles. End users can search, upload, edit, annotate and export expert-curated bioactivity data for further analysis, using an application programmable interface, database dump or tab-delimited text download options. To guide chemical biology and drug-repurposing applications, DTC version 2.0 includes updated clinical development information for the compounds and target gene-disease associations, as well as cancer-type indications for mutant protein targets, which are critical for precision oncology developments.

bay083.pdf