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Monte Carlo evaluation of accuracy and noise properties of two scatter correction methods for Tl-201 cardiac SPECT




TekijätNarita Y, Iida H, Eberl S, Nakamura T

KustantajaIEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC

Julkaisuvuosi1997

JournalIEEE Transactions on Nuclear Science

Tietokannassa oleva lehden nimiIEEE TRANSACTIONS ON NUCLEAR SCIENCE

Lehden akronyymiIEEE T NUCL SCI

Vuosikerta44

Numero6

Aloitussivu2465

Lopetussivu2472

Sivujen määrä8

ISSN0018-9499

DOIhttps://doi.org/10.1109/23.656453


Tiivistelmä
Two independent scatter correction techniques, transmission dependent convolution subtraction (TDCS) and triple-energy window (TEW) method, were evaluated in terms of quantitative accuracy and noise properties using Monte Carlo simulation (EGS4). Emission projections (primary, scatter and scatter plus primary) were simulated for three numerical phantoms for Tl-201. Data were reconstructed with ordered-subset EM algorithm including noise-less transmission data based attenuation correction. Accuracy of TDCS and TEW scatter corrections were assessed by comparison with simulated true primary data The uniform cylindrical phantom simulation demonstrated better quantitative accuracy with TDCS than with TEW (-2.0% vs 16.7%) and better S/N (6.48 vs 5.05). A uniform ring myocardial phantom simulation demonstrated better homogeneity with TDCS than TEW in the myocardium; i.e., anterior-to-posterior wall count ratios were 0.99 and 0.76 with TDCS and TEW, respectively. For the MCAT phantom, TDCS provided good visual and quantitative agreement with simulated true primary image without noticeably increasing the noise after scatter correction. Overall TDCS proved to be more accurate and less noisy than TEW, facilitating quantitative assessment of physiological functions with SPECT.



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