A1 Refereed original research article in a scientific journal
Monte Carlo evaluation of accuracy and noise properties of two scatter correction methods for Tl-201 cardiac SPECT
Authors: Narita Y, Iida H, Eberl S, Nakamura T
Publisher: IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
Publication year: 1997
Journal: IEEE Transactions on Nuclear Science
Journal name in source: IEEE TRANSACTIONS ON NUCLEAR SCIENCE
Journal acronym: IEEE T NUCL SCI
Volume: 44
Issue: 6
First page : 2465
Last page: 2472
Number of pages: 8
ISSN: 0018-9499
DOI: https://doi.org/10.1109/23.656453
Abstract
Two independent scatter correction techniques, transmission dependent convolution subtraction (TDCS) and triple-energy window (TEW) method, were evaluated in terms of quantitative accuracy and noise properties using Monte Carlo simulation (EGS4). Emission projections (primary, scatter and scatter plus primary) were simulated for three numerical phantoms for Tl-201. Data were reconstructed with ordered-subset EM algorithm including noise-less transmission data based attenuation correction. Accuracy of TDCS and TEW scatter corrections were assessed by comparison with simulated true primary data The uniform cylindrical phantom simulation demonstrated better quantitative accuracy with TDCS than with TEW (-2.0% vs 16.7%) and better S/N (6.48 vs 5.05). A uniform ring myocardial phantom simulation demonstrated better homogeneity with TDCS than TEW in the myocardium; i.e., anterior-to-posterior wall count ratios were 0.99 and 0.76 with TDCS and TEW, respectively. For the MCAT phantom, TDCS provided good visual and quantitative agreement with simulated true primary image without noticeably increasing the noise after scatter correction. Overall TDCS proved to be more accurate and less noisy than TEW, facilitating quantitative assessment of physiological functions with SPECT.
Two independent scatter correction techniques, transmission dependent convolution subtraction (TDCS) and triple-energy window (TEW) method, were evaluated in terms of quantitative accuracy and noise properties using Monte Carlo simulation (EGS4). Emission projections (primary, scatter and scatter plus primary) were simulated for three numerical phantoms for Tl-201. Data were reconstructed with ordered-subset EM algorithm including noise-less transmission data based attenuation correction. Accuracy of TDCS and TEW scatter corrections were assessed by comparison with simulated true primary data The uniform cylindrical phantom simulation demonstrated better quantitative accuracy with TDCS than with TEW (-2.0% vs 16.7%) and better S/N (6.48 vs 5.05). A uniform ring myocardial phantom simulation demonstrated better homogeneity with TDCS than TEW in the myocardium; i.e., anterior-to-posterior wall count ratios were 0.99 and 0.76 with TDCS and TEW, respectively. For the MCAT phantom, TDCS provided good visual and quantitative agreement with simulated true primary image without noticeably increasing the noise after scatter correction. Overall TDCS proved to be more accurate and less noisy than TEW, facilitating quantitative assessment of physiological functions with SPECT.
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