Influence of cardiovascular risk status on coronary flow reserve in healthy young men




Pitkanen OP, Raitakari OT, Ronnemaa T, Niinikoski H, Nuutila P, Iida H, Viikari JSA, Knuuti J

PublisherEXCERPTA MEDICA INC

1997

American Journal of Cardiology

AMERICAN JOURNAL OF CARDIOLOGY

AM J CARDIOL

79

12

1690

&

4

0002-9149

DOIhttps://doi.org/10.1016/S0002-9149(97)00226-9



To detect changes in vascular physiology associated with early atherosclerosis, we studied whether alterations in coronary flow reserve, as assessed by positron emission tomography imaging with intravenous dipyridamole, would be related to risk factor variables in healthy young men. The number of conventional risk variables correlated significantly with coronary flow reserve (r = -0.58, p = 0.0007), suggesting that alterations in functional vascular reactivity are related to the cardiovascular risk status already in healthy young men.



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