A1 Refereed original research article in a scientific journal
Influence of cardiovascular risk status on coronary flow reserve in healthy young men
Authors: Pitkanen OP, Raitakari OT, Ronnemaa T, Niinikoski H, Nuutila P, Iida H, Viikari JSA, Knuuti J
Publisher: EXCERPTA MEDICA INC
Publication year: 1997
Journal: American Journal of Cardiology
Journal name in source: AMERICAN JOURNAL OF CARDIOLOGY
Journal acronym: AM J CARDIOL
Volume: 79
Issue: 12
First page : 1690
Last page: &
Number of pages: 4
ISSN: 0002-9149
DOI: https://doi.org/10.1016/S0002-9149(97)00226-9
Abstract
To detect changes in vascular physiology associated with early atherosclerosis, we studied whether alterations in coronary flow reserve, as assessed by positron emission tomography imaging with intravenous dipyridamole, would be related to risk factor variables in healthy young men. The number of conventional risk variables correlated significantly with coronary flow reserve (r = -0.58, p = 0.0007), suggesting that alterations in functional vascular reactivity are related to the cardiovascular risk status already in healthy young men.
To detect changes in vascular physiology associated with early atherosclerosis, we studied whether alterations in coronary flow reserve, as assessed by positron emission tomography imaging with intravenous dipyridamole, would be related to risk factor variables in healthy young men. The number of conventional risk variables correlated significantly with coronary flow reserve (r = -0.58, p = 0.0007), suggesting that alterations in functional vascular reactivity are related to the cardiovascular risk status already in healthy young men.
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