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Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells




TekijätRamirez J, Martinez A, Lectez B, Lee SY, Franco M, Barrio R, Dittmar G, Mayor U

KustantajaPublic Library of Science

Julkaisuvuosi2015

Lehti: PLoS ONE

Tietokannassa oleva lehden nimiPLOS ONE

Lehden akronyymiPLOS ONE

Artikkelin numeroe0139083

Vuosikerta10

Numero10

Sivujen määrä24

ISSN1932-6203

eISSN1932-6203

DOIhttps://doi.org/10.1371/journal.pone.0139083


Tiivistelmä

These data cast light on the differential and common ubiquitination pathways between the embryonic and adult neurons, and hence will contribute to the understanding of the mechanisms by which neuronal function is regulated. The in vivo biotinylation methodology described here complements other approaches for ubiquitome study and offers unique advantages, and is poised to provide further insight into disease mechanisms related to the ubiquitin proteasome system.




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