A1 Refereed original research article in a scientific journal

Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells



Authors: Ramirez J, Martinez A, Lectez B, Lee SY, Franco M, Barrio R, Dittmar G, Mayor U

Publisher: Public Library of Science

Publication year: 2015

Journal: PLoS ONE

Journal name in source: PLOS ONE

Journal acronym: PLOS ONE

Article number: e0139083

Volume: 10

Issue: 10

Number of pages: 24

ISSN: 1932-6203

eISSN: 1932-6203

DOI: https://doi.org/10.1371/journal.pone.0139083


Abstract

These data cast light on the differential and common ubiquitination pathways between the embryonic and adult neurons, and hence will contribute to the understanding of the mechanisms by which neuronal function is regulated. The in vivo biotinylation methodology described here complements other approaches for ubiquitome study and offers unique advantages, and is poised to provide further insight into disease mechanisms related to the ubiquitin proteasome system.




Last updated on 26/11/2024 10:21:58 PM