A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Heterogeneity of Muscle Blood Flow and Metabolism: Influence of Exercise, Aging, and Disease States
Tekijät: Heinonen I, Koga S, Kalliokoski KK, Musch TI, Poole DC
Kustantaja: LIPPINCOTT WILLIAMS & WILKINS
Julkaisuvuosi: 2015
Journal: Exercise and Sport Sciences Reviews
Tietokannassa oleva lehden nimi: EXERCISE AND SPORT SCIENCES REVIEWS
Lehden akronyymi: EXERC SPORT SCI REV
Vuosikerta: 43
Numero: 3
Aloitussivu: 117
Lopetussivu: 124
Sivujen määrä: 8
ISSN: 0091-6331
eISSN: 1538-3008
DOI: https://doi.org/10.1249/JES.0000000000000044
The systematic increase in VO2 uptake and O-2 extraction with increasing work rates conceals a substantial heterogeneity of O-2 delivery (QO(2))-to- VO2 matching across and within muscles and other organs. We hypothesize that whether increased/decreased QO(2)/VO2 heterogeneity can be judged as "good" or "bad," for example, after exercise training or in aged individuals or with disease (heart failure, diabetes) depends on the resultant effects on O-2 transport and contractile performance.