B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä
The ''thio effect' on the hydrolysis and transesterification of ribonucleoside phosphoesters
Tekijät: Oivanen M, Ora M, Lonnberg H
Kustantaja: INST ORGANIC CHEM AND BIOCHEM
Julkaisuvuosi: 1996
Lehti:: Collection of Czechoslovak Chemical Communications
Tietokannassa oleva lehden nimi: COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
Lehden akronyymi: COLLECT CZECH CHEM C
Vuosikerta: 61
Aloitussivu: S1
Lopetussivu: S4
Sivujen määrä: 4
ISSN: 0010-0765
Tiivistelmä
The effects that replacing one of the non-bridging oxygens of ribonucleoside phosphoesters with sulfur exerts on the kinetics of phosphoester hydrolysis and intramolecular transesterification under various conditions are discussed. The experimental examples refer to the phosphoromonothioate analogs of uridylyl(3',5')uridine, uridine 2',3'-cyclic monophosphate, and uridine 2'- and 3'-monophosphates.
The effects that replacing one of the non-bridging oxygens of ribonucleoside phosphoesters with sulfur exerts on the kinetics of phosphoester hydrolysis and intramolecular transesterification under various conditions are discussed. The experimental examples refer to the phosphoromonothioate analogs of uridylyl(3',5')uridine, uridine 2',3'-cyclic monophosphate, and uridine 2'- and 3'-monophosphates.
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