A1 Refereed original research article in a scientific journal
Genetic polymorphism of sterol transporters in children with future gallstones
Authors: Markku J.Nissinen, Niina Pitkänen, Piia Simonen, Helena Gylling, Jorma Viikari, Olli Raitakari, Terho Lehtimäki, Markus Juonala, Mikko P. Pakarinen
Publisher: Elsevier B.V.
Publication year: 2018
Journal: Digestive and Liver Disease
Journal name in source: Digestive and Liver Disease
Volume: 50
Issue: 9
First page : 954
Last page: 960
Number of pages: 7
ISSN: 1590-8658
eISSN: 1878-3562
DOI: https://doi.org/10.1016/j.dld.2018.04.007
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/31920777
Conclusions
Risk trait of cholesterol metabolism (low phytosterols) in childhood favouring cholesterol gallstone disease later in adulthood is influenced by risk variant 19H of ABCG8 and obviously also other factors. NPC1L1 variants have minor influence on noncholesterol sterols.
Downloadable publication This is an electronic reprint of the original article. |