A1 Refereed original research article in a scientific journal

Genetic polymorphism of sterol transporters in children with future gallstones




AuthorsMarkku J.Nissinen, Niina Pitkänen, Piia Simonen, Helena Gylling, Jorma Viikari, Olli Raitakari, Terho Lehtimäki, Markus Juonala, Mikko P. Pakarinen

PublisherElsevier B.V.

Publication year2018

JournalDigestive and Liver Disease

Journal name in sourceDigestive and Liver Disease

Volume50

Issue9

First page 954

Last page960

Number of pages7

ISSN1590-8658

eISSN1878-3562

DOIhttps://doi.org/10.1016/j.dld.2018.04.007

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/31920777


Abstract
Conclusions

Risk trait of cholesterol metabolism (low phytosterols) in childhood favouring cholesterol gallstone disease later in adulthood is influenced by risk variant 19H of ABCG8 and obviously also other factors. NPC1L1 variants have minor influence on noncholesterol sterols.


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