A1 Refereed original research article in a scientific journal
The predictive adaptive response and metabolic syndrome: challenges for the hypothesis
Authors: Rickard IJ, Lummaa V
Publisher: ELSEVIER SCIENCE LONDON
Publication year: 2007
Journal: Trends in Endocrinology and Metabolism
Journal name in source: TRENDS IN ENDOCRINOLOGY AND METABOLISM
Journal acronym: TRENDS ENDOCRIN MET
Volume: 18
Issue: 3
First page : 94
Last page: 99
Number of pages: 6
ISSN: 1043-2760
DOI: https://doi.org/10.1016/j.tem.2007.02.004
Abstract
In humans and other mammals, maternal undernutrition or stress during gestation results in small offspring with permanently altered metabolism and tissue composition. It has been suggested that such responses might exist because in utero conditions provide a reliable 'prediction' of the environmental conditions that foetuses will eventually be exposed to during adulthood. Thus, some developmental responses to the early environment might improve an individual's evolutionary success in a similar future environment.
In humans and other mammals, maternal undernutrition or stress during gestation results in small offspring with permanently altered metabolism and tissue composition. It has been suggested that such responses might exist because in utero conditions provide a reliable 'prediction' of the environmental conditions that foetuses will eventually be exposed to during adulthood. Thus, some developmental responses to the early environment might improve an individual's evolutionary success in a similar future environment.
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