Low Expression of Nuclear Toll-like Receptor 4 in Laryngeal Papillomas Transforming into Squamous Cell Carcinoma
: Taru Ilmarinen, Jaana Hagström, Caj Haglund, Eeva Auvinen, Ilmo Leivo, Anne Pitkäranta, Leena-Maija Aaltonen
Publisher: SAGE PUBLICATIONS LTD
: 2014
: Otolaryngology - Head and Neck Surgery
: OTOLARYNGOLOGY-HEAD AND NECK SURGERY
: OTOLARYNG HEAD NECK
: 151
: 5
: 785
: 790
: 6
: 0194-5998
: 1097-6817
DOI: https://doi.org/10.1177/0194599814549730
Conclusion. The expression of TLR4 may serve as a predictive marker of malignant transformation in LPs. High immunoexpression of cytoplasmic TLR4 in LSCC was associated with a more aggressive disease.