Low Expression of Nuclear Toll-like Receptor 4 in Laryngeal Papillomas Transforming into Squamous Cell Carcinoma




Taru Ilmarinen, Jaana Hagström, Caj Haglund, Eeva Auvinen, Ilmo Leivo, Anne Pitkäranta, Leena-Maija Aaltonen

PublisherSAGE PUBLICATIONS LTD

2014

Otolaryngology - Head and Neck Surgery

OTOLARYNGOLOGY-HEAD AND NECK SURGERY

OTOLARYNG HEAD NECK

151

5

785

790

6

0194-5998

1097-6817

DOIhttps://doi.org/10.1177/0194599814549730



Conclusion. The expression of TLR4 may serve as a predictive marker of malignant transformation in LPs. High immunoexpression of cytoplasmic TLR4 in LSCC was associated with a more aggressive disease.



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