Low Expression of Nuclear Toll-like Receptor 4 in Laryngeal Papillomas Transforming into Squamous Cell Carcinoma - UTU Research Portal

A1 Refereed original research article in a scientific journal

Low Expression of Nuclear Toll-like Receptor 4 in Laryngeal Papillomas Transforming into Squamous Cell Carcinoma

Authors: Taru Ilmarinen, Jaana Hagström, Caj Haglund, Eeva Auvinen, Ilmo Leivo, Anne Pitkäranta, Leena-Maija Aaltonen

Publisher: SAGE PUBLICATIONS LTD

Publication year: 2014

Journal: Otolaryngology - Head and Neck Surgery

Journal name in source: OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Journal acronym: OTOLARYNG HEAD NECK

Volume: 151

Issue: 5

First page : 785

Last page: 790

Number of pages: 6

ISSN: 0194-5998

eISSN: 1097-6817

DOI: https://doi.org/10.1177/0194599814549730

Abstract

Conclusion. The expression of TLR4 may serve as a predictive marker of malignant transformation in LPs. High immunoexpression of cytoplasmic TLR4 in LSCC was associated with a more aggressive disease.