A1 Refereed original research article in a scientific journal

Role of the potassium/lysine cationic center in catalysis and functional asymmetry in membrane-bound pyrophosphatases



Authors: Artukka E, Luoto HH, Baykov AA, Lahti R, Malinen AM

Publisher: Portland Press Ltd.

Publication year: 2018

Journal: Biochemical Journal

Journal name in source: The Biochemical journal

Journal acronym: Biochem J

Volume: 475

Issue: 6

First page : 1141

Last page: 1158

Number of pages: 18

ISSN: 1470-8728

DOI: https://doi.org/10.1042/BCJ20180071

Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/30734070


Abstract
/Lys center was identified as part of the mechanism underlying this effect. These findings suggest that the mPPase homodimer possesses an asymmetry of active site performance that may be an ancient prototype of the rotational binding-change mechanism of F-type ATPases.

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Last updated on 2024-26-11 at 20:04