A1 Refereed original research article in a scientific journal

Humoral response to John Cunningham virus during pregnancy in multiple sclerosis




AuthorsM. Saraste, S. Atula, K. Hedman, S. Hurme, A. Jalkanen, M. Sneck, H.-M. Surcel, A.H. Maghzi, L. Airas

PublisherElsevier B.V.

Publication year2018

JournalMultiple Sclerosis and Related Disorders

Journal name in sourceMultiple Sclerosis and Related Disorders

Volume21

First page 11

Last page18

Number of pages8

ISSN2211-0348

eISSN2211-0356

DOIhttps://doi.org/10.1016/j.msard.2018.02.008

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/30545669


Abstract
Conclusions

JCV-Ab levels remain unaltered during MS pregnancy, while the total IgG concentration is reduced/diluted due to increasing plasma volumes during the course of pregnancy. This may imply a biologically significant alteration in the immune response to JCV during MS pregnancy.


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Last updated on 2024-26-11 at 20:29