A1 Refereed original research article in a scientific journal

Adventures in radiosynthesis of clinical grade [68Ga]Ga-DOTA-Siglec-9



Authors: Käkelä Meeri, Luoto Pauliina, Viljanen Tapio, Virtanen Helena, Liljenbäck Heidi, Jalkanen Sirpa, Knuuti Juhani, Roivainen Anne, Li Xiang-Guo

Publisher: ROYAL SOC CHEMISTRY

Publication year: 2018

Journal: RSC Advances

Journal name in source: RSC ADVANCES

Journal acronym: RSC ADV

Volume: 8

Issue: 15

First page : 8051

Last page: 8056

Number of pages: 6

ISSN: 2046-2069

eISSN: 2046-2069

DOI: https://doi.org/10.1039/c7ra12423f

Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/30431180


Abstract
We finally managed to establish a protocol for generating Good Manufacturing Practice (GMP)-grade gallium-68-labelled 1,4,7,0-tetraazacyclododecane-1,4,7,10-tetraacetic acid conjugated sialic acid-binding immunoglobulin-like lectin 9 motif containing peptide ([Ga-68]Ga-DOTA-Siglec-9), the first radiopharmaceutical for positron emission tomography imaging of vascular adhesion protein 1.

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Last updated on 2024-26-11 at 10:49