Azole antimycotics and drug interactions in the perioperative period
: Saari TI, Olkkola KT
Publisher: LIPPINCOTT WILLIAMS & WILKINS
: 2010
: Current Opinion in Anaesthesiology
: CURRENT OPINION IN ANESTHESIOLOGY
: CURR OPIN ANESTHESIO
: 4
: 23
: 4
: 441
: 448
: 8
: 0952-7907
DOI: https://doi.org/10.1097/ACO.0b013e32833a254d(external)
This review focuses on azole antimycotics and anesthetic drugs being used during the perioperative period and discusses the possible clinically significant drug-drug interactions. Azole antimycotics are amongst the strongest inhibitors of CYP-mediated drug metabolism. Anesthesiologists must be aware of the interaction potential of azole antimycotics to be able to adjust their perioperative strategies according to the patient's condition and concomitant medication.