A2 Refereed review article in a scientific journal
Azole antimycotics and drug interactions in the perioperative period
Authors: Saari TI, Olkkola KT
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Publication year: 2010
Journal: Current Opinion in Anaesthesiology
Journal name in source: CURRENT OPINION IN ANESTHESIOLOGY
Journal acronym: CURR OPIN ANESTHESIO
Number in series: 4
Volume: 23
Issue: 4
First page : 441
Last page: 448
Number of pages: 8
ISSN: 0952-7907
DOI: https://doi.org/10.1097/ACO.0b013e32833a254d
Abstract
This review focuses on azole antimycotics and anesthetic drugs being used during the perioperative period and discusses the possible clinically significant drug-drug interactions. Azole antimycotics are amongst the strongest inhibitors of CYP-mediated drug metabolism. Anesthesiologists must be aware of the interaction potential of azole antimycotics to be able to adjust their perioperative strategies according to the patient's condition and concomitant medication.
This review focuses on azole antimycotics and anesthetic drugs being used during the perioperative period and discusses the possible clinically significant drug-drug interactions. Azole antimycotics are amongst the strongest inhibitors of CYP-mediated drug metabolism. Anesthesiologists must be aware of the interaction potential of azole antimycotics to be able to adjust their perioperative strategies according to the patient's condition and concomitant medication.
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